Microencapsulation Yield Assessment Using TGA(Pages 1-11)

Carlos García Carmona1,2, Manuel J. Lis Arias2, Oscar Garcia Carmona2, Fabricio Maestá Bezerra3, Marc Pallarès Andreu1 and Noelia de la Cruz Díaz1

1GDE I+D+I, C/ Colom 564 Nau 1, 08228, Terrassa, Barcelona; 2Chemical Engineering Dept. ESEIAAT. UPC. Campus de Terrassa, Edificio TR1. C. Colom, 1, 08222, Terrassa, Spain; 3Federal University of Technology – Parana´, 635 Marcilio Dias Street, Apucarana, Parana´, Brazil

Abstract: In this study, microcapsules containing different contents of different kinds of fragrances and with a regular spherical shape, 2,0–8,0 µm diameter, were synthesized in various core:shell ratios. Mint and cuir fragrances were successfully encapsulated in poly(urea-formaldehyde) (PUF) shell via in-situ polymerization. This was confirmed by optical microscope, scanning electron microscope (SEM) and Fourier transform infrared spectroscopy (FTIR) studies. By observation from thermogravimetric analysis (TGA), it was found a relation between thermal gravimetric curves and the amount of fragrance encapsulated, which was later contrasted by ultraviolet-visible spectroscopy. In this way, comparatively, the yield percentage values can be quantitatively defined with a sufficient degree of accuracy by TGA method.

Keywords: Microcapsules, Drug-delivery, Thermo gravimetry and yield assessment.